Figure 6 from PTP4A2 Promotes Glioblastoma Progression and Macrophage Polarization under Microenvironmental Pressure

Phenotype of PTP4A2-KO and Ctrl tumors in the CT2A syngeneic model. A, Western blot analysis of Ctrl and PTP4A2-KO CT2A cells. B, Tumor volume with representative images of DAPI staining in CT2A tumor sections (left) and quantification (right). Permutation t test. C, Immunostaining of F4/80, MHC-II, and MRC1 with representative images (left) and quantification (right). D, Immunostaining of CD3 and FoxP3 with representative images (left) and quantification (right). Mann–Whitney U test. E, Immunostaining of CD31 and DAPI with representative images (left) and quantification (right). Permutation t test. n = 5–6 mice per group.