This work reports the draft genome sequence of the fermented food probiotic Bacillus subtilis strain S2, which has antibacterial activity against Micrococcus luteus, Vibrio harveyi, Staphylococcus aureus, Listeria monocytogenes, and Streptococcus mutans. From the de novo assembly, a genome with 4,438 open reading frames and an approximate size of 4,208,679 bp was obtained. Phylogenetically, B. subtilis S2 and B. subtilis SRCM103571 are closely related. The organism is known to produce two bacteriocins (uniqueness), Sublancin and Subtilosin A, as per genome analyses by antiSMASH and BAGEL-4.
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Jain et al. (2024) studied this question.
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