Sinus nodal denervation by targeting the superior paraseptal ganglionated plexus: randomized comparison of right-atrial and bi-atrial cardioneuroablation guided by ablation index
Authors
Discussion
Loading...
Member takes
Implication
Randomized trial demonstrates higher complete sinus nodal denervation with bi-atrial versus right-atrial cardioneuroablation in functional bradyarrhythmias, suggesting superior acute efficacy.
Key Points
- Complete sinus nodal denervation was achieved in 100% of bi-atrial cardioneuroablation patients versus 73% with right-atrial lesions, though the acute difference was not significant.
- Post-ablation sinus arrests reached 1.0±0.3 s with bi-atrial targeting versus 3.0±3.7 s after right-atrial ablation, evaluated by extracardiac vagus nerve stimulation.
- Randomized comparison of 22 patients with functional bradyarrhythmias evaluated right-atrial versus bi-atrial radiofrequency catheter ablation guided by the ablation index.
- Highlights that targeting the superior paraseptal ganglionated plexus from both atria may provide superior sinus nodal denervation, while post-ablation heart rate changes remain unreliable.
Cite This Study
Wichterle et al. (2024) studied this question.