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April 4, 2024ACS Applied Materials & Interfaces

Glycol Chitosan-Poly(lactic acid) Conjugate Nanoparticles Encapsulating Ciprofloxacin: A Mucoadhesive, Antiquorum-Sensing, and Biofilm-Disrupting Treatment Modality for Bacterial Keratitis

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SPSri Ganga PadagaBirla Institute of Technology and Science - Hyderabad CampusHBHimanshu BhattIndian Institute of Science Education and Research MohaliSCSanjay ChFroedtert Hospital

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Padaga et al. (2024) studied this question.

synapsesocial.com/papers/68e7055ab6db64358767fa92https://doi.org/10.1021/acsami.3c18061
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Fabrication and Assessment of Quorum Sensing Inhibitor Enhanced Ciprofloxacin <scp>HCl</scp> Nanoparticles for Anti‐Biofilm Ocular Drug Delivery2025
  2. 2A Triple‐Modal “One‐Stone‐for‐Three‐Birds” Strategy: Breaking Ocular Barriers to Combat Bacterial Keratitis With Antibacterial, Antioxidant and Anti‐Inflammatory2026
  3. 3Coaxial PCL-Core/PVA–Silk Fibroin-Shell Nanofibers for Sustained Ciprofloxacin Delivery and Antibacterial Activity: Direct Loading versus Chitosan Nanoparticle-Mediated Delivery2026
  4. 4Targeted Bacterial Keratitis Treatment with Polyethylene Glycol-Dithiothreitol-Boric Acid Hydrogel and Gatifloxacin2024
  5. 5Invasomes and Nanostructured Lipid Carriers for Targeted Delivery of Ceftazidime Combined with N-Acetylcysteine: A Novel Approach to Treat Pseudomonas aeruginosa-Induced Keratitis2025