March 15, 2024INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGYOpen Access

Effect of dengue infection on liver profile and hematological parameters

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MHMuthalibu Muhammed Hunais SSShaheed Shiffana WUWalawe Gamage Nimalka Udayangani

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Implication

Comparative evaluation reveals elevated liver enzymes and reduced platelet counts in dengue patients, highlighting aspartate aminotransferase as a primary marker of acute liver injury.

Key Points

Aspartate aminotransferase showed the most pronounced elevation among hepatic enzymes, marking widespread liver injury alongside marked decreases in both platelet and leukocyte counts.
Serum aspartate aminotransferase reached 105.6 IU/L in acute patients, rising 3.4-fold above control levels while remaining strongly correlated with alanine aminotransferase elevations.
Assessment of blood samples from 169 acute cases and 60 healthy controls highlights aspartate aminotransferase as a key marker of liver injury, supporting routine profile monitoring.

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Hunais et al. (2024) studied this question.

synapsesocial.com/papers/68e73dc3b6db6435876b6d8a https://doi.org/10.33086/ijmlst.v6i1.5039

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Implication

Comparative evaluation reveals elevated liver enzymes and reduced platelet counts in dengue patients, highlighting aspartate aminotransferase as a primary marker of acute liver injury.

Effect of dengue infection on liver profile and hematological parameters

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Implication

Key Points

Cite This Study

Effect of dengue infection on liver profile and hematological parameters

Discussion

Member takes

Implication

Key Points

Cite This Study

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