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March 1, 2024Cell ReportsOpen Access

Neuromuscular organoids model spinal neuromuscular pathologies in C9orf72 amyotrophic lateral sclerosis

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Authors

CGChong GaoQSQinghua ShiPXPan Xue

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Cite This Study

Gao et al. (2024) studied this question.

synapsesocial.com/papers/68e7604eb6db6435876d759bhttps://doi.org/10.1016/j.celrep.2024.113892
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Neural Organoid Models as a Platform for Studying Disease Mechanisms in Amyotrophic Lateral Sclerosis2026
  2. 2Advances and Challenges in the Use of Spinal Cord Organoids in ALS2026
  3. 3Aberrant evoked calcium signaling and nAChR cluster morphology in a SOD1 D90A hiPSC-derived neuromuscular model2024 · 3 citations
  4. 4Altered Inflammatory Signature in a <scp><i>C9ORF72</i></scp>‐<scp>ALS iPSC</scp>‐Derived Motor Neuron and Microglia Coculture Model2025 · 4 citations
  5. 5Cellular and axonal transport phenotypes due to the C9ORF72 HRE in iPSC motor and sensory neurons2024 · 4 citations