Angiosarcoma (AS) is a rare variant of malignant soft tissue sarcoma, representing less than 1% of all soft tissue sarcomas.1 Among the histopathological subtypes of AS, epithelioid angiosarcoma (EAS) is characterized by epithelioid morphology, with polygonal or spherical cells containing eosinophilic cytoplasm.2 Tumors where over 80% of the cells are epithelioid are typically classified as EAS.3 EAS usually manifests during adulthood, particularly around the seventh decade of life.2 Approximately 12% of cutaneous AS is cutaneous EAS, yet detailed studies on clinical presentations are lacking.
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Tokuchi et al. (2024) studied this question.
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