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October 12, 2025Open Access

Hyperuricemia as an Early Indicator of Cardiovascular Risk in the General Population

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Authors

FAFady Al-AzemBSB. SchraderJSJoachim Schrader

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Overview

Prospective cohort study links hyperuricemia with higher cardiovascular disease incidence, suggesting early intervention may reduce risk.

Key Points

  • Higher serum uric acid levels correlate with increased cardiovascular events, indicating a potential independent risk factor.
  • Participants with elevated uric acid had incidence rates of coronary artery disease at 8.4%, compared to 3.3% for normal levels.
  • The study analyzed data from 4,082 individuals, demonstrating the role of uric acid in cardiovascular risk assessments.
  • Routine uric acid measurements could help identify individuals at higher risk for cardiovascular complications and support early treatment.

Cite This Study

Al-Azem et al. (2025) studied this question.

synapsesocial.com/papers/68ebc91af2c3e4d8d926e2aehttps://doi.org/10.20944/preprints202510.0460.v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hyperuricemia as an Early Indicator of Cardiovascular Risk in the General Population2025
  2. 2Uric Acid and Cardiovascular Disease2026
  3. 3THE IMPACT OF HYPERURICEMIA ON CARDIOVASCULAR RISK. REVIEW OF THE EXISTING LITERATURE2025
  4. 4The association between serum uric acid level and heart failure and mortality in the early period of ST-elevation acute myocardial infarction2014 · 12 citations
  5. 5Serum Uric Acid and Cardiovascular Mortality2000 · 1,524 citations