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October 13, 2025Yemeni Journal For Medical SciencesOpen Access

Evaluation of Diuretic and Antibacterial Activities of Tribulus terrestris Ethanolic Extract

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Authors

AAAhmed Al-mohamadiITImadeldin M Taj-EldinDIDoa’a Anwar Ibrahim

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Overview

This study evaluates the diuretic and antibacterial effects of Tribulus terrestris in rodent models and in vitro, indicating its potential in treating renal disorders.

Key Points

  • Ethanol extract of Tribulus terrestris showed significant dose-dependent diuretic effects in rodent models, enhancing urine output dramatically.
  • At 450 mg/kg, urine output and sodium excretion increased significantly (p < 0.05 and p < 0.01, respectively), comparable to the diuretic furosemide.
  • In vitro testing revealed moderate antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa, highlighting its potential therapeutic applications.
  • These findings suggest that Tribulus terrestris may provide a complementary approach for addressing renal disorders, meriting further clinical investigation.

Cite This Study

Al-mohamadi et al. (2025) studied this question.

synapsesocial.com/papers/68ece2abd1bb2827d1297329https://doi.org/10.20428/yjms.v19i10.3301
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sub-Acute Toxicity Evaluation and Antiurolithiatic Activity of Tribulus terrestris Ethanol Extract in Rats2026
  2. 2Phytochemical analysis and antibacterial activity of Tribulus terrestris L. against selected bacterial strains2026
  3. 3A TRADITIONAL DRUG TRIBULUS TERRESTRIS AS A RENAL REGULATOR UTILISES IN MODERN THERAPY2026
  4. 4Inhibitory Potential of Tribulus terrestris on Calcium Oxalate Crystals, Struvite Crystals and Bacterial Pathogens: A Preliminary Investigation2024 · 1 citations
  5. 5Bioactive Compounds, Antibacterial, Antioxidant, Anticancer, and Antidiabetic Potential of the Seed and Leaves of Tribulus terrestris2025