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October 15, 2025

Table S5 from Exon Skipping of Ste20-Like Kinase Enhances Glycolysis and Tumor Progression by Activating Enolase 1–Mediated Phosphoenolpyruvate Production

Zeyu Chen Jingyu Liao Chang Zhu Ruizhi Chang Huifang Liang Zeyang Ding Zhao Huang Xiaoping Chen Jia Liang Bixiang Zhang

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Key Points

Enhanced phosphoenolpyruvate production leads to increased tumor progression, driven by enolase 1 activation.
The study identifies differentially expressed peptides linked to metabolic changes in tumor cells.
Assessment used examination of exon skipping effects on glycolysis pathways; future work needed for clinical applications.
These findings highlight metabolic pathways as new targets for cancer treatment strategies.

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Implication

Exon skipping enhances phosphoenolpyruvate production in tumor cells, indicating potential metabolic intervention.

Abstract

Differentially Expressed Peptides in LiP-SMap

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Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/68f199bfde32064e504dcb7a https://doi.org/10.1158/0008-5472.30363369

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Table S4 from Exon Skipping of <i>Ste20-</i><i>Like</i><i> Kinase</i> Enhances Glycolysis and Tumor Progression by Activating Enolase 1–Mediated Phosphoenolpyruvate Production2025
2Figure S3 from Exon Skipping of <i>Ste20-</i><i>Like</i><i> Kinase</i> Enhances Glycolysis and Tumor Progression by Activating Enolase 1–Mediated Phosphoenolpyruvate Production2025
3Figure S2 from Exon Skipping of <i>Ste20-</i><i>Like</i><i> Kinase</i> Enhances Glycolysis and Tumor Progression by Activating Enolase 1–Mediated Phosphoenolpyruvate Production2025
4Table S3 from Exon Skipping of <i>Ste20-</i><i>Like</i><i> Kinase</i> Enhances Glycolysis and Tumor Progression by Activating Enolase 1–Mediated Phosphoenolpyruvate Production2025
5Figure S5 from Exon Skipping of <i>Ste20-</i><i>Like</i><i> Kinase</i> Enhances Glycolysis and Tumor Progression by Activating Enolase 1–Mediated Phosphoenolpyruvate Production2025

Figure S6 from Exon Skipping of <i>Ste20-</i><i>Like</i><i> Kinase</i> Enhances Glycolysis and Tumor Progression by Activating Enolase 1–Mediated Phosphoenolpyruvate Production2025
Figure S8 from Exon Skipping of <i>Ste20-</i><i>Like</i><i> Kinase</i> Enhances Glycolysis and Tumor Progression by Activating Enolase 1–Mediated Phosphoenolpyruvate Production2025
Figure S7 from Exon Skipping of <i>Ste20-</i><i>Like</i><i> Kinase</i> Enhances Glycolysis and Tumor Progression by Activating Enolase 1–Mediated Phosphoenolpyruvate Production2025