⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

October 15, 2025

Table S3 from Exon Skipping of Ste20-Like Kinase Enhances Glycolysis and Tumor Progression by Activating Enolase 1–Mediated Phosphoenolpyruvate Production

Zeyu Chen Jingyu Liao Chang Zhu Ruizhi Chang Huifang Liang Zeyang Ding Zhao Huang Xiaoping Chen Jia Liang Bixiang Zhang

View at Publisher

Ask AI

Bookmark

Share

Key Points

Exon skipping enhances glycolysis and tumor progression through increased phosphoenolpyruvate production.
Treatment of MHCC-97H cells revealed significant changes in metabolite expression levels with H3B-8800 compared to DMSO.
The study assesses the impact of enolase 1 activation on tumor metabolism and growth.
Findings indicate a potential therapeutic target in the metabolic pathways governing tumor progression.

Implication

Research shows that exon skipping activates enolase 1 to boost phosphoenolpyruvate production, suggesting a link to tumor progression.

Abstract

No abstract yet. The journal hasn't published one we can show.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/68f199bfde32064e504dcb79 https://doi.org/10.1158/0008-5472.30363375

View at Publisher

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Table S4 from Exon Skipping of <i>Ste20-</i><i>Like</i><i> Kinase</i> Enhances Glycolysis and Tumor Progression by Activating Enolase 1–Mediated Phosphoenolpyruvate Production2025
2Figure S1 from Exon Skipping of <i>Ste20-</i><i>Like</i><i> Kinase</i> Enhances Glycolysis and Tumor Progression by Activating Enolase 1–Mediated Phosphoenolpyruvate Production2025
3Table S5 from Exon Skipping of <i>Ste20-</i><i>Like</i><i> Kinase</i> Enhances Glycolysis and Tumor Progression by Activating Enolase 1–Mediated Phosphoenolpyruvate Production2025
4Figure S2 from Exon Skipping of <i>Ste20-</i><i>Like</i><i> Kinase</i> Enhances Glycolysis and Tumor Progression by Activating Enolase 1–Mediated Phosphoenolpyruvate Production2025
5Figure S8 from Exon Skipping of <i>Ste20-</i><i>Like</i><i> Kinase</i> Enhances Glycolysis and Tumor Progression by Activating Enolase 1–Mediated Phosphoenolpyruvate Production2025

Figure S5 from Exon Skipping of <i>Ste20-</i><i>Like</i><i> Kinase</i> Enhances Glycolysis and Tumor Progression by Activating Enolase 1–Mediated Phosphoenolpyruvate Production2025
Figure S6 from Exon Skipping of <i>Ste20-</i><i>Like</i><i> Kinase</i> Enhances Glycolysis and Tumor Progression by Activating Enolase 1–Mediated Phosphoenolpyruvate Production2025
Figure S3 from Exon Skipping of <i>Ste20-</i><i>Like</i><i> Kinase</i> Enhances Glycolysis and Tumor Progression by Activating Enolase 1–Mediated Phosphoenolpyruvate Production2025