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October 19, 2025Journal of Medical Microbiology

A nanoluciferase-tagged Schmallenberg virus (SBV): an efficient tool for measuring and tracking viral infection dynamics

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Authors

FSFranziska SickAAAndrea AebischerMBMartin Beer

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Overview

Development of a tagged SBV shows improved tracking of viral replication and neutralization assays.

Key Points

  • The nluc-tagged SBV allows rapid tracking of viral replication, enhancing research capabilities.
  • In vitro studies show no attenuation in the nluc-tagged virus compared to the parental strain.
  • A new serum neutralization assay utilizing nanoluciferase activity was successfully developed.
  • The study offers a promising approach for high-throughput assays in viral research.

Cite This Study

Sick et al. (2025) studied this question.

synapsesocial.com/papers/68f43ef4854d1061a58abe27https://doi.org/10.1099/jmm.0.002084
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