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November 8, 2025Open Access

A phage-derived reconfigurable effector associated with an actinobacterial contractile nanomachine tailors bacterial responses to competition

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Authors

TNToshiki NagakuboTNTatsuya NishiyamaSAShumpei Asamizu

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Overview

Observational analysis shows enhanced competition in actinobacteria, indicating phage-derived effectors can reprogram bacterial responses.

Key Points

  • Enhanced adaptation in actinobacteria through phage-derived effectors.
  • The effectors interact with ribosome-containing subcellular fractions to modify physiology.
  • Assessment using contractile injection systems reveals diverse effector functionalities.
  • Highlights the potential for phage elements in bacterial adaptation to varied conditions.

Cite This Study

Nagakubo et al. (2025) studied this question.

synapsesocial.com/papers/690e8b6ca5b062d7a4e73660https://doi.org/10.1101/2025.11.06.686954
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