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This research aims to explore the relationship between tumor protein p53 expression and various stages of breast cancer.

November 13, 2025Scientific ReportsOpen Access

Analysis of tumor protein p53 expression levels in different stages of breast cancer

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Analysis reveals correlation of tumor protein p53 expression with breast cancer stage, indicating its significance as a biomarker.

This research aims to explore the relationship between tumor protein p53 expression and various stages of breast cancer.
Examined 70 individuals diagnosed with breast cancer
Extracted RNA samples and evaluated Tp53 expression using real-time RT-PCR
Analyzed data with SPSS software
Up-regulation of p53 expression found in breast cancer subjects
Stage 4 showed highest Tp53 expression, while stage 1 had none
Increased Tp53 expression correlates with tumor aggressiveness
Patients aged 40 or above had higher Tp53 expression levels
Individuals with familial history of breast cancer had elevated Tp53 expression

Arab et al. (2025) studied this question.

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