November 11, 2025BMC Infectious DiseasesOpen Access

The quantity and severity of adverse drug reactions experienced by patients with multi-drug resistant tuberculosis in the Ugu District

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Authors

SRSerisha RamasirUniversity of KwaZulu-Natal FOFrasia Oosthuizen VBVarsha Bangalee

Discussion

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Implication

Observational analysis reported safety issues like ototoxicity and hypothyroidism in patients with multi-drug resistant tuberculosis, suggesting enhanced pharmacovigilance systems are necessary.

Key Points

Safety concerns include adverse drug reactions such as ototoxicity and hypothyroidism in patients receiving MDR-TB treatment.
Key findings highlighted that new drugs like bedaquiline and linezolid contributed significantly to adverse reactions.
The observational analysis examined clinical charts over three years in patients with multi-drug resistant tuberculosis.
Increased monitoring and established pharmacovigilance systems may improve therapy responses and drug safety.

Cite This Study

Ramasir et al. (2025) studied this question.

synapsesocial.com/papers/69252e90c0ce034ddc355f74 https://doi.org/10.1186/s12879-025-11901-7

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Implication

Observational analysis reported safety issues like ototoxicity and hypothyroidism in patients with multi-drug resistant tuberculosis, suggesting enhanced pharmacovigilance systems are necessary.

The quantity and severity of adverse drug reactions experienced by patients with multi-drug resistant tuberculosis in the Ugu District

Discussion

Member takes

Implication

Key Points

Cite This Study

The quantity and severity of adverse drug reactions experienced by patients with multi-drug resistant tuberculosis in the Ugu District

Discussion

Member takes

Implication

Key Points

Cite This Study

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Also Consider