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November 11, 2025BiomedicinesOpen Access

Preventive and Therapeutic Interventions in Solar Elastosis and Photoaging: A Comprehensive Systematic Review

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Authors

FLFrancesco LeonforteTPTiziano PergolizziVNVito Nicosia

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Overview

Systematic review reveals therapeutic interventions improve photoaging outcomes in adults, suggesting need for randomized controlled trials.

Key Points

  • The review synthesizes evidence on interventions for solar elastosis and photoaging, focusing on their clinical efficacy.
  • Systematic review of articles from PubMed, Scopus, ProQuest, and Web of Science.
  • Inclusion of clinical studies on adults with solar elastosis and photoaging signs.
  • Primary outcomes evaluated were clinical and histopathological improvements.
  • Twenty-two studies with 608 participants were included in the analysis.
  • Device-assisted therapies like laser and radiofrequency showed consistent improvements in photoaging outcomes.
  • Patient satisfaction with interventions was high, despite mild and transient adverse events.

Cite This Study

Leonforte et al. (2025) studied this question.

synapsesocial.com/papers/69252e90c0ce034ddc35612ehttps://doi.org/10.3390/biomedicines13112758
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Photoaging: molecular mechanisms, clinical impact, and treatment strategies2025
  2. 2Topical and systemic skin aging interventions: Evidence, pitfalls and perspectives2026 · 3 citations
  3. 3Exploring Cellular and Molecular Mechanisms Involved in UV-inducedSkin Photo-aging2026
  4. 4Photoaging: Update on Pathogenesis, Prevention, and Treatment2026
  5. 5Longevity in Aesthetic Dermatology: Review of the Literature2026