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November 11, 2025Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca Food Science and TechnologyOpen Access

Integrated Phytochemical Characterization and in-vitro Antioxidant, Anti-inflammatory and Safety Evaluation of Selected Medicinal Plants

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Authors

PSPawan SharmaBMBinita MandalNSNikhat Shaikh

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Overview

In vitro evaluation revealed antioxidant and anti-inflammatory effects of Matricaria chamomilla and safety in medicinal plants, highlighting their potential therapeutic benefits.

Key Points

  • To assess the anti-inflammatory, antioxidant potential, and safety of selected medicinal plants.
  • Conducted in-vitro antioxidant assays including ABTS, DPPH, FRAP, lipid peroxidation, and nitric oxide tests.
  • Performed safety assessment using the Hen’s Egg Test – Chorioallantoic Membrane (HET-CAM) assay.
  • Utilised FTIR spectroscopy for functional group evaluation.
  • M. chamomilla exhibited highest carbohydrate, protein, and flavonoid content.
  • F. asafoetida showed lowest DPPH IC50 at 2.280±0.041 µg/mL.
  • All extracts displayed potential for DNA protection against oxidative damage with irritation scores below 1.

Cite This Study

Sharma et al. (2025) studied this question.

synapsesocial.com/papers/69252e96c0ce034ddc3562f5https://doi.org/10.15835/buasvmcn-fst:2025-0076
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