What type of study is this?

This is a In Vitro Study study.

November 30, 2025Scientific ReportsOpen Access

Decoding the anti-inflammatory properties of sesquiterpene coumarins from the active fractions of Ferula assa-foetida through integrated experimental and in silico analyses

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Authors

MAMubarak A. Alamri GSGamal A. Soliman MAMohammed A Alamri

Discussion

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Implication

In vivo and in vitro evaluations of anti-inflammatory activity showed significant effects, indicating potential therapeutic uses of sesquiterpene coumarins.

Key Points

Nitric oxide generation was significantly inhibited by compounds from ethyl acetate and hexane fractions.
Spectroscopic investigation confirmed the structure of auraptene, umbelliprenin, galbanic acid, and kamolonol.
Molecular docking and molecular dynamic simulation analyses revealed target genes for active compounds.
Findings highlight the potential of network pharmacology to explore anti-inflammatory compounds, warranting further studies.

Cite This Study

Alamri et al. (2025) studied this question.

synapsesocial.com/papers/692b94581d383f2b2a378fff https://doi.org/10.1038/s41598-025-26010-3

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Implication

In vivo and in vitro evaluations of anti-inflammatory activity showed significant effects, indicating potential therapeutic uses of sesquiterpene coumarins.

Decoding the anti-inflammatory properties of sesquiterpene coumarins from the active fractions of Ferula assa-foetida through integrated experimental and in silico analyses

Discussion

Member takes

Implication

Key Points

Cite This Study

Decoding the anti-inflammatory properties of sesquiterpene coumarins from the active fractions of Ferula assa-foetida through integrated experimental and in silico analyses

Discussion

Member takes

Implication

Key Points

Cite This Study

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Also Consider