Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
November 1, 2025Neuro-OncologyOpen Access

EXTH-39. Inhibition of glioma cell invasiveness by sonodynamic therapy

View Full Paper
Ask AI
Bookmark
Share

Authors

SMSteen MadsenKGKeya GuptaSLSophia Laurel

Discussion

Loading...

Member takes

Overview

Sonodynamic therapy reduces tumor migration in glioblastomas, indicating a non-invasive method to limit infiltration.

Key Points

  • Sonodynamic therapy significantly reduces tumor invasiveness in glioblastomas, and may become a novel treatment modality.
  • Reduction in migration distances was observed with higher ultrasonic activation, enhancing glioma treatment efficacy.
  • Assessment using 3D spheroid migration assay demonstrated the effectiveness of sonodynamic therapy against tumor cells.
  • Future studies should focus on treatment optimization and validation using in vivo models for translational application.

Cite This Study

Madsen et al. (2025) studied this question.

synapsesocial.com/papers/69254362c0ce034ddc358219https://doi.org/10.1093/neuonc/noaf201.1373
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sonodynamic therapy inhibition of invasive glioma cells from tumor spheroids2026 · 1 citations
  2. 2Sonodynamic Therapy With Orally Absorbable Nanomedicine for Brain Tumor2025
  3. 3Preclinical evidence of sonodynamic therapy in glioblastoma and challenges towards clinical translation: a review of the literature2026 · 1 citations
  4. 4Sonodynamic Therapy: Porphyrin-Based Sensitizers and Low-Intensity Ultrasound for Precision Treatment of Glioblastoma2026
  5. 5EXTH-55. Targeting Malignant Gliomas with 5-ALA Sonodynamic Therapy: In Vitro Efficacy, HIFU-Delivered In Vivo Treatment, and Berberine Potentiation2025