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November 28, 2025Bulletin of the National Research Centre/Bulletin of the National Research CenterOpen Access

Vitamin D and type 2 diabetes mellitus: mechanisms, clinical evidence, and future perspectives

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Authors

HSHanan B. Saadon

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Overview

Review analyzes clinical trials linking vitamin D and glycemic control in type 2 diabetes, highlighting inflammation's role.

Key Points

  • Elevated vitamin D levels are linked to lower type 2 diabetes risk with a 30% to 40% reduction.
  • Clinical trials show inconsistent results for blood sugar regulation despite vitamin D's benefits.
  • Evidence suggests vitamin D improves insulin response and reduces inflammation in diabetes management.
  • Highlights the need for future studies to consider genetic and lifestyle factors in diabetes treatment.

Cite This Study

Hanan B. Saadon (2025) studied this question.

synapsesocial.com/papers/6928f0f9a65b730b9ea798efhttps://doi.org/10.1186/s42269-025-01377-5
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Vitamin D and type 2 diabetes mellitus: mechanisms, clinical evidence, and future perspectives2025 · 4 citations
  2. 2The Impact of Vitamin D on Type 2 Diabetes Mellitus: Exploring Its Role in Glucose Metabolism and Insulin Sensitivity2025
  3. 3The Impact of Vitamin D Supplementation on Fasting Plasma Glucose, Insulin Sensitivity, and Inflammation in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis2025 · 12 citations
  4. 4The Analysis Study of The Effect Vitamin D to Risk for Type 2 Diabetes Mellitus in People with Pre-Diabetes : A Comprehensive Systematic Review2024
  5. 5The Impact of Vitamin D in Primary Prevention of Type 2 Diabetes – A Systematic Review2025