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November 30, 2025Journal of Clinical MedicineOpen Access

Hormonal and Osmoregulatory Responses in Intraoperative High-Volume Diuresis During Off-Pump Coronary Artery Bypass Grafting: An Exploratory Cohort Study

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Overview

Exploratory cohort study shows high-volume diuresis impacts urine output and hormonal regulation in cardiac surgery, indicating challenges in fluid management.

Key Points

  • Intraoperative high-volume diuresis occurred in 54.2% of cases, highlighting significant hormonal regulation involvement.
  • Logistic regression identified low body mass index, reduced albumin, and lower copeptin as key predictors of diuresis.
  • Observation utilized logistic regression and ROC curves to assess hormonal and biochemical parameters perioperatively.
  • Implications suggest electrolyte imbalances emerge during surgery, prompting a need for enhanced monitoring of fluid management.

Cite This Study

A 2025 study studied this question.

synapsesocial.com/papers/692b94581d383f2b2a378ef4https://doi.org/10.3390/jcm14238395
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hormonal and Osmoregulatory Responses in Intraoperative High-Volume Diuresis During Off-Pump Coronary Artery Bypass Grafting: An Exploratory Cohort Study2025
  2. 2The impact of intraoperative hypotension on postoperative acute kidney injury, mortality and length of stay following off-pump coronary artery bypass grafting surgery: a single-center retrospective cohort study2024 · 10 citations
  3. 3Antidiuretic Hormone and Cardiovascular Responses During and After Coronary Artery Bypass Surgery1993 · 7 citations
  4. 4Renal implications of off-pump coronary artery bypass grafting: A retrospective cohort study analyzing postoperative creatinine levels2023
  5. 5Fluid Overload after Coronary Artery Bypass Grafting Surgery Increases the Incidence of Post-Operative Complications2011 · 26 citations