Why the study?
How do postoperative plasma antidiuretic hormone (ADH) concentrations correlate with hemodynamic parameters in patients undergoing coronary artery bypass surgery?
Population
23 patients undergoing coronary artery bypass surgery
Design
Cohort
Follow-up
up to 2nd postoperative day
Key result
Early after coronary artery bypass surgery, high plasma ADH concentrations in patients requiring IABP directly reflected hemodynamic derangement, while later secretion was influenced by surgical stress.
Authors
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May mark early hemodynamic instability in post-CABG IABP patients; leaves open therapeutic relevance of ADH modulation.
Observational (n=23)
How do postoperative plasma antidiuretic hormone (ADH) concentrations correlate with hemodynamic parameters in patients undergoing coronary artery bypass surgery?
High plasma ADH concentrations early after CABG reflect hemodynamic derangement in patients requiring IABP, whereas later ADH secretion is likely driven by postsurgical stress.
Amano et al. (1993) conducted an observational in Coronary artery bypass surgery (n=23). Requirement of intraaortic balloon pumping (IABP) or inotropic agents vs. No requirement of IABP or inotropic agents was evaluated on Correlations in changes of postoperative plasma antidiuretic hormone (ADH) concentrations and hemodynamic parameters. Early after coronary artery bypass surgery, high plasma ADH concentrations in patients requiring IABP directly reflected hemodynamic derangement, while later secretion was influenced by surgical stress.
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