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November 28, 2025HLA

The HLA‐C*12:04:04 Allele Identified by Next Generation Sequencing in an Individual From Tamil Nadu, India

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Key Points

The unique HLA-C*12:04:04 allele was revealed through next generation sequencing techniques, indicating genetic diversity.
This allele differs from HLA-C*12:04:02:02 due to a single synonymous nucleotide substitution in exon 5.
Next generation sequencing enabled precise identification of genetic variations within the HLA locus, showcasing its relevance in population genetics.
Understanding these alleles can help in studying genetic predispositions to diseases in diverse populations.

Implication

Novel HLA-C*12:04:04 identified via next generation sequencing, indicating a single nucleotide change from HLA-C*12:04:02:02.

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Cite This Study

Divya Shree (2025) studied this question.

synapsesocial.com/papers/692e3da16c9b3ab28c187d13 https://doi.org/10.1111/tan.70497

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