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May 1, 2026

A Novel HLA Class I Allele, HLA-C*15:299, Identified by Next-Generation Sequencing in an Indian Individual.

Samir Agarwal Shikha Kumari Neha Bairagi Manu Bamal Vandana Rana

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Key Points

Identify a novel HLA class I allele, HLA-C*15:299, through next-generation sequencing.
Utilized next-generation sequencing to analyze HLA alleles in an Indian individual.
HLA-C*15:299 was identified with two nucleotide changes compared to HLA-C*15:02:01:01 across exons 2 and 3.

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Implication

Novel allele HLA-C*15:299 differs by nucleotide changes, indicating genetic diversity in individuals.

Abstract

HLA-C*15:299 differs from HLA-C*15:02:01:01 by two nucleotide changes across exons 2 and 3.

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Cite This Study

Agarwal et al. (2026) studied this question.

synapsesocial.com/papers/6a095c2c7880e6d24efe22a6 https://doi.org/10.1111/tan.70751

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