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May 29, 2026HLA

Characterisation of the Novel HLA‐C*12:459 Allele Using Third‐Generation Sequencing Methods

Maxime Raz Patrice Dunoyer Justine Demortier Coralie Frassati Pascal Pedini

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Key Points

The aim is to characterize the novel HLA-C*12:459 allele and its genetic differences from HLA-C*12:02:02:01.
Used third-generation sequencing to analyze HLA alleles.
Identified specific nucleotide substitutions in exon 2.
HLA-C*12:459 differs from HLA-C*12:02:02:01 by a single nucleotide substitution.

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Implication

Analysis characterizes the HLA-C*12:459 allele, revealing a single substitution in exon 2.

Abstract

HLA‐C*12:459 differs HLA‐C*12:02:02:01 by a single substitution in exon 2.

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Cite This Study

Raz et al. (2026) studied this question.

synapsesocial.com/papers/6a1bd2675783ba022b6fddcb https://doi.org/10.1111/tan.70775

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