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December 4, 2025Brain and BehaviorOpen Access

Role of Probiotics in Management of Depressive Symptoms and Cognitive Impairment in Patients With Depression: An Updated Analysis of Trials

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Authors

AKAashish KumarUIUmer IqbalMAMuhammad Aniq Amir

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Overview

Meta-analysis shows probiotics significantly reduce depressive symptoms and cognitive impairment in depression, suggesting their therapeutic potential.

Key Points

  • Patients receiving probiotics had significant alleviation of cognitive symptoms (p = 0.01) compared to placebo.
  • Probiotic treatment also led to a reduction in depressive symptoms (p = 0.03), indicating strong efficacy.
  • This analysis included seven randomized control trials adhering to PRISMA guidelines, ensuring rigorous standards.
  • Therapeutic potential of probiotics in clinical settings merits further investigation to comprehend underlying mechanisms.

Cite This Study

Kumar et al. (2025) studied this question.

synapsesocial.com/papers/6930dc5fea1aef094cca1d9fhttps://doi.org/10.1002/brb3.71108
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