Cross-sectional study uncovers immune signatures linked to heavy menstrual bleeding, suggesting immune activity may play a significant role.
Although no single immune cell type was independently associated with HMB compared with controls, the observed significant correlations among CD4⁺, CD8⁺, CD56⁺, and CD68⁺ highlight the interconnected nature of endometrial immune activity.
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Mangla et al. (2025) studied this question.
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