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December 4, 2025Molecular Biology ReportsOpen Access

Glutamine reprogramming affects the tumor microenvironment and immune response in hepatocellular carcinoma

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Authors

YSYong Sun

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Overview

Analysis reveals glutamine metabolism influences tumor microenvironment and immune response in hepatocellular carcinoma, suggesting new therapeutic strategies.

Key Points

  • Glutamine metabolism affects the immune response and tumor microenvironment in HCC.
  • Study shows that altered glutamine pathways impact HCC growth and progression, emphasizing clinical significance.
  • Analysis focuses on metabolic pathways and immune modulation related to glutamine in liver cancer.
  • Findings highlight the need for research into innovative therapeutic strategies for managing HCC.

Cite This Study

Yong Sun (2025) studied this question.

synapsesocial.com/papers/6930dc92ea1aef094cca2a67https://doi.org/10.1007/s11033-025-11309-1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Glutamine metabolism, a double agent combating or fuelling hepatocellular carcinoma2024 · 31 citations
  2. 2Glutamine as a context-dependent regulator controlling metabolism and immunity in triple-negative breast cancer2026
  3. 3Glutamine sequestration promotes tumor growth and immune evasion through elevation of arginine methylation in hepatocellular carcinoma2026
  4. 4Research progress on amino acid metabolic reprogramming in hepatocellular carcinoma2026
  5. 5Unraveling the role of glutamine metabolism in cancer: from cell death mechanisms to tumor microenvironment modulation2026