Prevalence of Point-of-Care Ultrasound Abnormalities and Raised Serum N-terminal Pro-B-type Natriuretic Peptide in Early-onset Preeclampsia

( Anesth Analg . 2025. doi: 10.1213/ANE.0000000000007650) Preeclampsia is a complex pregnancy disorder that can cause serious risks for both mothers and infants. Its early-onset form (EOPE), defined as occurring before 34 weeks of gestation, is particularly severe and remains less understood compared with late-onset preeclampsia (LOPE). Previous research in LOPE suggested that pulmonary interstitial syndrome (PIS), a condition marked by excess lung fluid detected through ultrasound, was associated with elevated left ventricular end-diastolic pressure (LVEDP), a marker of cardiac strain assessed by echocardiography. This study sought to investigate whether the same relationship exists in EOPE and to explore the broader prevalence of heart and lung abnormalities using point-of-care ultrasound (POCUS) and laboratory markers.