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December 8, 2025Blood

Impact of social determinants on inpatient outcomes in hairy cell leukemia: A national cohort study

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Authors

CDCanan DiricanMMMichael Maroules

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Overview

National cohort analysis shows that social determinants influence inpatient mortality and healthcare disparities in hairy cell leukemia.

Key Points

  • This research explores how social determinants impact inpatient outcomes for patients with hairy cell leukemia.
  • Retrospective cross-sectional analysis of adult hospitalizations for hairy cell leukemia
  • Utilized the 2020-2022 National Inpatient Sample database
  • Examined variables including race/ethnicity, insurance type, and socio-economic status
  • Applied multivariable logistic regression, negative binomial regression, and gamma regression for various outcomes
  • Identified 4,825 hospitalizations related to hairy cell leukemia
  • Insurance status significantly influenced mortality rates among self-pay patients and those with Medicare
  • Female patients showed lower hospitalization costs and shorter lengths of stay
  • Hospital type and neighborhood income were linked to resource utilization and inpatient efficiency

Cite This Study

Dirican et al. (2025) studied this question.

synapsesocial.com/papers/693624dd4fa91c937236d1d1https://doi.org/10.1182/blood-2025-8037
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Abstract 3570: Long-term mortality trends in hairy cell leukemia: A comprehensive U.S. population analysis (1999-2023)2026
  2. 2Real-world survival analysis of adolescent and young adult patients with hairy cell leukemia in the United States.2026
  3. 3Inpatient outcomes of diffuse large B-cell lymphoma: Racial and socioeconomic disparities in a nationally representative sample2025
  4. 4Social determinants of health and long-term survival in chronic lymphocytic leukemia/small lymphocytic lymphoma: A population-based analysis of 118,667 patients2025
  5. 5Socioeconomic, racial, and hospital-level disparities in inpatient mortality among patients with plasma cell dyscrasias: A 2016-2022 nationwide analysis from the national inpatient sample2025