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December 8, 2025Blood

Social determinants of health and outcomes in patients with acute leukemia: Interim results from a prospective, single institution study

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Authors

MOMaire OkoniewskiJWJianzheng WuHMHeather Male

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Overview

Prospective analysis reveals socioeconomic factors affect outcomes in acute leukemia patients, suggesting targeted interventions are needed.

Key Points

  • This research aims to understand how social determinants of health affect outcomes for patients with acute leukemia.
  • Prospective enrollment of patients at the University of Kansas Medical Center diagnosed with acute leukemia.
  • Patients underwent surveys regarding social determinants of health, including food insecurity and financial toxicity.
  • Outcome measures included clinical trial enrollment, missed appointments, and ICU admissions.
  • 61 patients were enrolled at interim analysis, with a median age of 61 years.
  • 54% of pre-screened patients enrolled in clinical trials, with significant differences in enrollment based on financial toxicity and disability.
  • 98% of patients enrolled were alive at day 30 post-diagnosis.

Cite This Study

Okoniewski et al. (2025) studied this question.

synapsesocial.com/papers/69362f5d4fa91c937236dbefhttps://doi.org/10.1182/blood-2025-6403
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Abstract 2485: Role of social determinants of health on survival in children with acute lymphoblastic leukemia in a Southern California cohort2026
  2. 2Prospective observational cohort study to collect granular social determinants of health data for hematopoietic cell transplant patients2025
  3. 3Abstract PR011: Investigating the interplay among allostatic load, social determinants of health, and treatment outcomes in chronic myeloid leukemia patients2024
  4. 4Abstract PS4-09-11: Associations of patient-reported social determinants of health (SDOH) with treatment deferral and clinic no-show rates in a diverse population of patients with breast cancer2026
  5. 5Abstract A010: Improving social determinants of health (SDoH) screening and intervention in a pediatric hematology/oncology clinic: A quality improvement initiative2025