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December 8, 2025BloodOpen Access

Prospective observational cohort study to collect granular social determinants of health data for hematopoietic cell transplant patients

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Authors

WFWarren Fingrut

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Overview

Prospective cohort study reveals social and financial barriers for patients undergoing hematopoietic cell transplant, indicating significant financial toxicity risks.

Key Points

  • To collect and analyze granular social determinants of health data for patients undergoing hematopoietic cell transplant.
  • Conducted a single center, prospective observational cohort study
  • Collected data from patients who received financial approval for hematopoietic cell transplant
  • Assessed various social and financial barriers faced by patients across different ancestries
  • High enrollment rate with 401 out of 424 screened patients participating
  • 54 patients reported at least one social barrier and 173 reported at least one financial barrier
  • Significant differences in barriers identified between European and non-European ancestry patients

Cite This Study

Warren Fingrut (2025) studied this question.

synapsesocial.com/papers/69362f7d4fa91c937236e436https://doi.org/10.1182/blood-2025-6163
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Social determinants of health and outcomes in patients with acute leukemia: Interim results from a prospective, single institution study2025
  2. 2The feasibility of collecting social determinants of health in the national multi-center GRASP sickle cell gene therapy trial2025
  3. 3Social determinants of health (SDOH) and barriers to allogeneic hematopoietic stem cell transplantation (HCT) in acute myeloid leukemia (AML) in a community setting.2026
  4. 4Can we perform allogeneic hematopoietic cell transplantation (HCT) safely in patients with limited social supports and substantial psychosocial complexity?2025
  5. 5Financial toxicity in allogeneic haematopoietic stem cell transplant patients from a social determinants of health perspective2024 · 3 citations