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December 8, 2025Blood

Acute lymphoid leukemia burden attributable to occupational benzene exposure from 1990-2021: Global patterns, trends, and implications for prevention

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Authors

SGSunitha GeddadaSDSamyak Dhruv

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Overview

Global analysis estimates occupational exposure to benzene increases acute lymphoid leukemia burden, suggesting urgent need for prevention measures.

Key Points

  • Quantify the global burden of acute lymphoid leukemia attributable to occupational benzene exposure from 1990 to 2021.
  • Conducted a global analysis using standardized global burden of disease methodology.
  • Derived mortality, years of life lost, and years lived with disability from various health databases.
  • Estimated population-attributable fractions using pooled relative risks from meta-analyses.
  • Deaths attributable to benzene exposure rose from 355 in 1990 to 525 in 2021.
  • Years of life lost increased from 19,508 to 26,846 during the same period.
  • Findings indicated a higher burden among females and in low-SDI regions.

Cite This Study

Geddada et al. (2025) studied this question.

synapsesocial.com/papers/69362f364fa91c937236d2cchttps://doi.org/10.1182/blood-2025-6833
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