Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 8, 2025Blood

Hematopoietic stem cell transplantation for relapsed classical Hodgkin lymphoma: A benchmark Study on 19,498 patients from the EBMT lymphoma working party

View Full Paper
Ask AI
Bookmark
Share

Authors

MFMathilde FekomSGSebastian GiebelMAMahmoud Aljurf

Discussion

Loading...

Member takes

Overview

Benchmark analysis reveals hematopoietic stem cell transplantation improves progression free survival in Hodgkin lymphoma patients with Brentuximab use.

Key Points

  • This research assesses the outcomes of hematopoietic stem cell transplantation for relapsed Hodgkin lymphoma.
  • Analysis of EBMT registry data for 19,498 patients from 2010 to 2022
  • Comparison of outcomes for auto-HSCT and allo-HSCT across three time periods
  • Multivariate analysis to identify survival factors
  • 2-year progression free survival increased from 63% to 73% for auto-HSCT
  • Brentuximab vedotin use associated with improved PFS
  • Younger age and Karnofsky score >90 positively influenced survival outcomes

Cite This Study

Fekom et al. (2025) studied this question.

synapsesocial.com/papers/69362f3d4fa91c937236d4d8https://doi.org/10.1182/blood-2025-4521
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hematopoietic stem cell transplantation for DLBCL: a report from the European Society for Blood and Marrow Transplantation on more than 40,000 patients over 32 years2024 · 29 citations
  2. 2Trends in transplantation for patients with myelodysplastic syndrome across recent decades: A registry-based study on behalf of the chronic malignancies working of the EBMT2025
  3. 3Allogeneic stem cell transplantation for major T-cell lymphoma entities: an analysis of the EBMT-lymphoma working party2026 · 3 citations
  4. 4Long‐term outcomes after allogeneic versus autologous haematopoietic stem cell transplantation for T‐lymphoblastic lymphoma2026
  5. 5The role of hematopoietic stem cell transplantation in peripheral T-cell lymphoma not otherwise specified2025