What type of study is this?

This is a Cohort Study study (also classified as: Cross-Sectional Study, Human Clinical Trial).

What question did this study set out to answer?

This study aims to explore healthcare professionals' perspectives on the treatment and management of AL amyloidosis.

December 8, 2025Blood

Health care professionals (HCPs) perspectives on treatment and management of light chain (AL) amyloidosis: An international cross-sectional survey study

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Authors

PMPaolo MilaniUniversity of Pavia

Discussion

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Implication

International survey reveals HCPs prefer daratumumab and dexamethasone as first-line therapy for AL amyloidosis, emphasizing clinical criteria for management.

Key Points

This study aims to explore healthcare professionals' perspectives on the treatment and management of AL amyloidosis.
Conducted an international online survey through ARC from April to July 2025.
Surveyed 55 HCPs treating AL amyloidosis, focusing on FLT and SLT preferences.
Collected data on demographic, clinical criteria, and trial participation.
88% of HCPs prefer daratumumab-based regimens as FLT for AL amyloidosis.
Less than 10% utilize ASCT as FLT, indicating a shift from previous preferences.
Most HCPs are uncomfortable using dFLC criteria for trial eligibility.

Cite This Study

Paolo Milani (2025) studied this question.

synapsesocial.com/papers/69362f484fa91c937236d6c2 https://doi.org/10.1182/blood-2025-7493

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Implication

International survey reveals HCPs prefer daratumumab and dexamethasone as first-line therapy for AL amyloidosis, emphasizing clinical criteria for management.

Health care professionals (HCPs) perspectives on treatment and management of light chain (AL) amyloidosis: An international cross-sectional survey study

Discussion

Member takes

Implication

Key Points

Cite This Study

Health care professionals (HCPs) perspectives on treatment and management of light chain (AL) amyloidosis: An international cross-sectional survey study

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider