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December 8, 2025BloodOpen Access

Race-based disparities in hemorrhagic stroke mortality with underlying coagulopathies: A CDC-wonder analysis (1999–2020)

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Authors

MSMuhammad Asjad SaleemASAyesha Saleem

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Overview

Analysis shows recent racial and regional disparities in mortality trends for hemorrhagic stroke with coagulopathies, highlighting inequities in care.

Key Points

  • This research aims to examine the racial and regional disparities in mortality rates from hemorrhagic stroke with coagulopathies.
  • Analyzed CDC WONDER mortality data from 1999 to 2020
  • Used ICD-10 codes for hemorrhagic stroke and coagulopathies
  • Calculated age-adjusted mortality rates per 100,000
  • Employed Joinpoint regression to assess trends
  • Estimated average annual percent change across demographics
  • A total of 32,696 hemorrhagic stroke deaths were recorded from 1999 to 2020
  • The age-adjusted mortality rate slightly declined from 0.675 in 1999 to 0.659 in 2020
  • Black individuals had the highest mortality rate among racial groups in 1999, differing by 2020
  • Rural areas consistently showed lower mortality rates compared to urban areas
  • The South region experienced the greatest improvement in mortality rates over the years

Cite This Study

Saleem et al. (2025) studied this question.

synapsesocial.com/papers/69362f4e4fa91c937236d900https://doi.org/10.1182/blood-2025-6639
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Abstract TP180: Trends and Disparities in Hemorrhagic Stroke-associated Mortality Among Adults in the United States: A Centers for Disease Control and Prevention (CDC) WONDER Analysis (1999-2023)2026
  2. 2Abstract WP161: Comparative Trends in Mortality from Ischemic and Hemorrhagic Stroke in the United States, 1999–20202026
  3. 3Stroke Mortality in the United States from 1968 to 2023: A CDC WONDER Analysis2025 · 8 citations
  4. 4Hemostasis in crisis: Two-decade trends of mortality due to coagulation defects in the u.S. population; A CDC- wonder database analysis2025
  5. 5Five‐Decade Mortality Trends in Ischemic Stroke in the United States: A CDC WONDER Analysis2025 · 6 citations