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December 8, 2025Blood

Cardiopulmonary complications during pregnancy as a risk factor for cesarean delivery in a two center, sickle cell disease pregnancy cohort

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Authors

RARia AroraALAmy LuoJSJayla Scott

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Overview

Pregnancy complications raise cesarean delivery rates in sickle cell disease, suggesting a need for careful management.

Key Points

  • This study aims to identify cardiopulmonary complications that lead to cesarean delivery in sickle cell disease pregnancies.
  • Analyzed data from two medical centers and included singleton pregnancies with SCD
  • Examined delivery modes and associated complications during pregnancy
  • Used chi-square and Kruskal-Wallis tests for statistical analysis
  • Cesarean delivery rate was 45% in the cohort
  • Cardiopulmonary complications significantly associated with emergent cesarean delivery
  • Emergent cesarean linked to higher adverse birth outcomes like NICU admission

Cite This Study

Arora et al. (2025) studied this question.

synapsesocial.com/papers/69362f514fa91c937236d98chttps://doi.org/10.1182/blood-2025-2945
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pregnancy related complications and placenta pathology in pregnant women with sickle cell disease2025 · 1 citations
  2. 2High rates of severe maternal morbidity and preterm birth among pregnant individuals with sickle cell disease, a nationwide study from 2020-20242025
  3. 3Pregnancy outcomes among women with sickle cell disease: A propensity score-matched analysis approach using the national inpatient sample (2017-2022)2025
  4. 4Increased risk of venous thromboembolism and hypertensive disorders during pregnancy in sickle cell disease patients: A meta-analysis focused on actionable outcomes2025
  5. 5Retrospective Analysis of Transfusions on Sickle Cell–Related Morbidity in Pregnancy2024