What question did this study set out to answer?

This study aims to evaluate maternal morbidity and economic outcomes associated with sickle cell disease during pregnancies.

December 8, 2025BloodOpen Access

Pregnancy outcomes among women with sickle cell disease: A propensity score-matched analysis approach using the national inpatient sample (2017-2022)

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Authors

RMRichard MansourLouisiana State University in Shreveport

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Implication

Retrospective cohort analysis evaluates maternal morbidity and economic outcomes in pregnancies with sickle cell disease, suggesting increased risks and healthcare costs.

Key Points

This study aims to evaluate maternal morbidity and economic outcomes associated with sickle cell disease during pregnancies.
Conducted a retrospective cohort study using data from the National Inpatient Sample (2017-2022)
Employed propensity score matching to compare deliveries of women with and without sickle cell disease
Analyzed outcomes using logistic regression for binary outcomes and generalized linear models for continuous outcomes.
Pregnancies with sickle cell disease had higher odds of preeclampsia, cesarean delivery, and severe maternal morbidity
Women with sickle cell disease experienced longer hospital stays and increased hospital charges
Findings indicate a significant burden of sickle cell disease on maternal health and healthcare resources.

Cite This Study

Richard Mansour (2025) studied this question.

synapsesocial.com/papers/69362f6c4fa91c937236df9b https://doi.org/10.1182/blood-2025-6218

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Implication

Retrospective cohort analysis evaluates maternal morbidity and economic outcomes in pregnancies with sickle cell disease, suggesting increased risks and healthcare costs.

Pregnancy outcomes among women with sickle cell disease: A propensity score-matched analysis approach using the national inpatient sample (2017-2022)

Discussion

Member takes

Implication

Key Points

Cite This Study

Pregnancy outcomes among women with sickle cell disease: A propensity score-matched analysis approach using the national inpatient sample (2017-2022)

Discussion

Member takes

Implication

Key Points

Cite This Study

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