Retrospective analysis shows increased mortality and worse outcomes in patients with first-time acute chest syndrome and pulmonary embolism, indicating need for careful management.
Key Points
This study aims to analyze the in-hospital outcomes of patients with first-time acute chest syndrome who have preexisting pulmonary embolism.
Retrospective cohort analysis using the United States National Inpatient Sample from 2016-2022.
Patients identified with ICD-10 codes for first episode acute chest syndrome and preexisting pulmonary embolism.
Primary outcome was in-hospital mortality; secondary outcomes included length of stay, resource utilization, and interventions.
2.45% of patients with first-time acute chest syndrome had preexisting pulmonary embolism.
Patients with pulmonary embolism had over a 6-times increase in odds of mortality (OR=6.95).
There was an average increase in length of stay by 3.43 days and hospital charges by $47,236.