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December 8, 2025BloodOpen Access

The role of palliative care in sickle cell disease: A single database literature review of contemporary outcomes data

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Authors

WCWilliam CiuryloAKAnand Karnad

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Overview

Literature review reveals benefits of multidisciplinary palliative care for sickle cell disease, pointing to resource allocation needs.

Key Points

  • To assess the role of palliative care in managing patients with sickle cell disease and evaluating outcomes.
  • Conducted a single database review using MEDLINE via PubMed to find relevant literature.
  • Reviewed articles published in English between 2004 and 2024.
  • Performed a descriptive analysis in accordance with the PRISMA-ScR checklist.
  • Screened articles for content suitability and stratified based on conclusions.
  • Identified seven relevant articles from 2004 to 2014 and seven from 2014 to 2024.
  • Three articles suggested palliative care benefits for sickle cell disease patients in both periods.
  • One cross-sectional study found limited implementation of inpatient palliative care for sickle cell disease patients.
  • No articles examined specific outcomes for sickle cell patients receiving palliative care.

Cite This Study

Ciurylo et al. (2025) studied this question.

synapsesocial.com/papers/69362f744fa91c937236e273https://doi.org/10.1182/blood-2025-6519
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sickle Cell Disease Providers' Perspectives on Palliative Care2024 · 1 citations
  2. 2Clinical outcomes in hospitalized sickle cell patients with palliative care consults2025
  3. 3Patient outcomes for sickle cell disease with support staff-driven interventions: A scoping review2025
  4. 4Top Ten Tips Palliative Care Clinicians Should Know About Sickle Cell Disease2026
  5. 5Assessing Involvement and Training of Academic Palliative Care Programs in the Care of Patients with Sickle Cell Disease: A Nationwide Survey2026