What question did this study set out to answer?

This research aims to explore the relationship between thrombotic risk, chronic kidney disease, and proteinuria in sickle cell disease.

December 8, 2025BloodOpen Access

Associations between chronic kidney disease, proteinuria, and thrombotic risk in SCD

View Full Paper

Ask AI

Bookmark

This research aims to explore the relationship between thrombotic risk, chronic kidney disease, and proteinuria in sickle cell disease.
Examined diagnoses using SNOMED data and ICD-10 codes in the ASH RC Data Hub.
Used Chi-square tests to compare conditions by age group.
Conducted a generalized linear mixed model analysis to assess VTE risk factors.
27.0% of participants diagnosed with VTE; 28.1% with CKD; 24.7% with proteinuria.
VTE risk associated with younger age, female sex, and certain sickle cell subtypes.
Microalbuminuria and proteinuria linked to increased VTE odds, independent of CKD.

Authors

No takes yet. Share an insight, caveat, or question.

Analysis reveals increased thrombotic risk in sickle cell disease linked to chronic kidney disease and proteinuria.

Sehl et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark