Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 6, 2025ACS Applied Materials & Interfaces

Assembled Gold Superstructure Triggered Synergistic Apoptosis/Ferroptosis via Combined Photo-Enzyme Therapy

View Full Paper
Ask AI
Bookmark
Share

Authors

HCHao ChenGZGuangrong ZhengYYYuanjun Yu

Discussion

Loading...

Member takes

Overview

Observational analysis reveals enhanced therapeutic efficacy in tumors via ferroptosis, oxidative stress, and gold nanoparticles.

Key Points

  • Dual activation of ferroptosis and apoptosis occurs, improving overall therapeutic outcomes with combined photo-enzyme therapy.
  • Gold nanoparticles significantly enhance the photothermal effect, increasing therapeutic efficacy in the tumor microenvironment.
  • NIR-triggered multifunctional nanoplatform integrates polydopamine and doxorubicin, promoting oxidative stress through hydroxyl radicals.
  • This approach highlights the importance of novel therapies in overcoming drug resistance in cancer treatment.

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/694020fd2d562116f28fb6a7https://doi.org/10.1021/acsami.5c20328
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Synergistic chemo-photothermal therapy using doxorubicin-loaded gold nanorods for enhanced apoptosis in lung cancer cells2025
  2. 2Synergistic Chemo-Photothermal Therapy Using Doxorubicin-Loaded Gold Nanorods for Enhanced Apoptosis in Lung Cancer Cells2025
  3. 3PD-L1 Aptamer-Functionalized Gold Nanorods for Targeted Combined Chemo-Photothermal Therapy in Breast Cancer.2025
  4. 4Targeted chemo‐phototherapy in red light with novel doxorubicin and iron(III) complex‐functionalized gold nanoconjugate (Dox‐Fe@FA‐AuNPs)2024 · 3 citations
  5. 5Water-Soluble DOX·HCl Delivery Nanoplatform for Efficient Photothermal Therapy with Chemotherapy: Polydopamine and Mesoporous Silica-Coated Gold Nanorods2025