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December 5, 2025Transplantation

Cumulative Risk Assessment for De Novo and Recurrent Nonliver Cancer After Liver Transplantation Based on Pretransplant Cancer Experience

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Authors

ALAlex Y. LiuAEAhmed Elhawary

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Overview

Cohort analysis reports higher cancer recurrence rates in liver transplant patients with previous malignancy, indicating urgent need for post-transplant cancer screening.

Key Points

  • Recurrent cancer is more prevalent following liver transplantation in patients with prior malignancy, showing significant rates.
  • Cumulative incidence of cancer post-LT is markedly higher, reaching 59.7% for PTM patients compared to 37.6% for those without.
  • Analysis of 1,105 liver transplant recipients reveals high recurrence rates of skin and liver cancers as major contributors.
  • Robust cancer screening after liver transplantation is critical due to the association of PTM with elevated cancer risk post-transplant.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/694022532d562116f28fc2e7https://doi.org/10.1097/tp.0000000000005576
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