Complete Revascularization with Multivessel PCI for Myocardial Infarction
Key result
Complete revascularization reduces CV death or MI versus culprit-only PCI in multivessel STEMI.
Why the study?
Does complete revascularization with multivessel PCI reduce cardiovascular death or myocardial infarction compared to culprit-lesion-only PCI in patients with STEMI and multivessel coronary artery disease?
Population
Patients with STEMI and multivessel coronary artery disease
Comparison
Complete revascularization vs culprit-lesion-only PCI
Authors
Discussion
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Member takes
Implication
Supports complete revascularization as standard in STEMI with multivessel disease; strengthens RCT evidence for guidelines.
Key Points
- To compare the effects of complete revascularization versus culprit-lesion-only PCI in patients with STEMI and multivessel coronary artery disease.
- Compared complete revascularization with culprit-lesion-only PCI
- Included patients diagnosed with STEMI and multivessel coronary artery disease
- Ascertained outcomes of cardiovascular death and myocardial infarction
- Complete revascularization significantly reduced the risk of cardiovascular death or myocardial infarction
- It also reduced the risk of cardiovascular death, myocardial infarction, or ischemia-driven revascularization
Structured PICO
Does complete revascularization with multivessel PCI reduce cardiovascular death or myocardial infarction compared to culprit-lesion-only PCI in patients with STEMI and multivessel coronary artery disease?
P
Population
Patients with STEMI and multivessel coronary artery disease
I
Intervention
Complete revascularization with multivessel PCI
C
Comparator
Culprit-lesion-only PCI
O
Outcome
Composite of cardiovascular death or myocardial infarctioncomposite
In patients with STEMI and multivessel disease, complete revascularization is superior to culprit-lesion-only PCI for reducing the composite of cardiovascular death or myocardial infarction.
Cite This Study
Mehta et al. (2019) studied this question. Complete revascularization in patients with STEMI and multivessel disease significantly reduced the risk of cardiovascular death or myocardial infarction compared to culprit-lesion-only PCI.