The Prognostic Value of Cardiac Troponin in Acute Ischemic Stroke Patients With Heart Failure: A Comparative Study Across Age Groups

Hence, this research aims to establish the correlation between cardiac troponin and results in acute ischemic stroke (AIS) patients with heart failure. It examines 367 AIS patients stratified into 2 age groups: 65–74 years and ≥75 years. According to the findings, independent ambulation at admission or discharge signifies less severe strokes National Institutes of Health Stroke Scale. That is, the characteristics that are important for the stroke severity in patients of different ages are different: while the patients aged 75 and older, the important predictors are peripheral vascular disease and increased heart rate, the stroke severity in the younger age is predicted by smoking history and increased serum creatinine. Further, the article examines the value of troponin in a consecutive series of 1145 AIS patients and demonstrates that increased troponin is an independent predictor of in-hospital mortality. Mortality of the troponin-positive patients is significantly high with an odds ratio of 4.28. Moreover, the second trial on 200 AIS patients demonstrated that the cardiac troponin isoforms size is an independent predictor of major adverse cardiac events, odds ratio of 9.76. A study of 151,972 reaffirms the relationship between high troponin levels, increased stroke severity, and worse clinical prognosis. In conclusion, the current work fosters the significance of evaluating cardiac troponin in AIS patients with heart failure for enhanced mortality and adverse cardiovascular events’ risk estimation.