Key result
Adding digitoxin to standard care is linked to fewer deaths or heart failure hospitalizations in HFrEF.
May support digitoxin addition in HFrEF; leaves open confirmation in randomized trials.
GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text].
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Kumar et al. (2026) studied this question. Adding digitoxin to standard care reduced the composite of death or first worsening heart failure hospitalization in patients with HFrEF at a median of 36 months.
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