In HFrEF, adding digitoxin to standard care reduced a composite of death or first worsening HF hospitalization at a median 36 mo

Key Result

Adding digitoxin to standard care reduced the composite of death or first worsening heart failure hospitalization in patients with HFrEF at a median of 36 months.

Key Points

• Evaluate the effect of adding digitoxin to standard care on heart failure outcomes in HFrEF.
• Clinical trial design targeting heart failure patients with reduced ejection fraction
• Standard care treatment alongside digitoxin administration
• Assessment of composite outcomes including death and hospitalization rates
• Digitoxin addition led to a reduced rate of the composite outcome of death or first worsening hospitalization at 36 months.
• Significant improvement observed in heart failure management metrics.