Key result
Atrial pacing to 140 bpm cuts LVEF ~33% alongside declines in GLS, LVEDV, and LVESV.
Why the study?
Current understanding of how heart rate influences echocardiographic measurements of left ventricular function and volume remains incomplete.
Does increasing heart rate via atrial pacing alter echocardiographic measures of left ventricular function and volume in patients with permanent pacemakers?
Does increasing heart rate via atrial pacing alter echocardiographic measures of left ventricular function and volume in patients with permanent pacemakers?
Increasing heart rate significantly reduces echocardiographic measures of LV function and volume, highlighting the need to account for heart rate during clinical interpretation.
No takes yet. Share an insight, caveat, or question.
Heart rate must be considered when interpreting GLS and LVEF on echo; leaves open standardization of rate-adjusted norms.
Woelfert et al. (2025) studied this question. As heart rate increased from 60 to 140 beats/min, GLS, LVEF, LVEDV, and LVESV decreased by 32%, 33%, 31%, and 10%, respectively, highlighting a significant impact on LV function.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: