Key result
Captopril reduced functional mitral regurgitation in dilated heart failure, requiring high doses (50-100 mg/day) for added benefit over standard treatment.
Why the study?
Does captopril reduce functional mitral regurgitation in patients with dilated heart failure?
Does captopril reduce functional mitral regurgitation in patients with dilated heart failure?
High-dose captopril (50-100 mg/day) provides additive benefits over conventional treatment in reducing functional mitral regurgitation in dilated heart failure.
High-dose captopril may reduce functional mitral regurgitation; leaves open confirmation of additive benefit in contemporary dilated HF.
Captopril is efficacious in reducing functional mitral regurgitation in dilated heart failure. Patients require and must tolerate high doses (50-100 mg/day) for additive effects over supervised conventional treatment to occur.
No takes yet. Share an insight, caveat, or question.
Seneviratne et al. (1994) studied this question. Captopril reduced functional mitral regurgitation in dilated heart failure, requiring high doses (50-100 mg/day) for added benefit over standard treatment.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: