Key result
No relationship was found between plasma homocysteine levels and carotid or femoral artery wall thickness or stiffness in patients at risk for cardiovascular disease.
Why the study?
Does hyperhomocysteinemia increase arterial wall thickness and stiffness compared to other cardiovascular risk factors and healthy controls?
Population
Patients at risk for atherosclerotic disease, including 19 homozygous and 14 heterozygous for cystathionine…
Design
Cross-sectional
Authors
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No association with arterial thickness or stiffness observed; leaves open any causal role and requires prospective confirmation.
Does hyperhomocysteinemia increase arterial wall thickness and stiffness compared to other cardiovascular risk factors and healthy controls?
Plasma homocysteine levels do not significantly correlate with arterial wall thickness and have only a marginal influence on arterial stiffness, unlike age, smoking, and blood pressure.
Smilde et al. (1998) studied this question. No relationship was found between plasma homocysteine levels and carotid or femoral artery wall thickness or stiffness in patients at risk for cardiovascular disease.
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