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February 6, 20260 citationsOpen Access

Randomised Controlled Trial on the Additive Effect Between Calcium Hydroxide and Sodium Hypochlorite in an Inter-Visit Root Canal Dressing

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NBNidambur V BallalNRNamith RaiPSPadmaja A Shenoy

Key Points

  • The research aims to determine the antimicrobial effects of combined calcium hydroxide and sodium hypochlorite during root canal treatment.
  • Randomised controlled trial design
  • Comparison between combined NaOCl/Ca(OH) dressing and saline slurry
  • Assessment of microbial load in root canals
  • Evaluation of inflammatory response in periapical tissues
  • Combined NaOCl/Ca(OH) dressing significantly reduced microbial load
  • No apparent inflammatory response observed in periapical tissues
  • Findings suggest improved effectiveness compared to saline slurry

Abstract

Aim: To assess whether there was an additive antimicrobial effect between calcium hydroxide (Ca(OH)) and sodium hypochlorite (NaOCl) in an inter-visit root canal dressing. Conclusions: Placing a combined NaOCl/Ca(OH) dressing significantly reduced the microbial load in the root canals of teeth with primary apical periodontitis compared to a conventional slurry prepared with saline solution, without causing any apparent inflammatory response in the periapical tissues. Trial registeration: CTRI/2020/10/028484 (Clinical Trials Registry India).

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Cite This Study

Ballal et al. (2025) studied this question.

synapsesocial.com/papers/698585fe8f7c464f23009c93https://doi.org/10.5167/uzh-284559
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